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Tumour seeding in the tract of percutaneous renal tumour biopsy: a report on seven cases from a UK tertiary referral centre

  • Philip S. Macklin,
  • Mark E. Sullivan,
  • Charles R. Tapping,
  • David W. Cranston,
  • Guy M. Webster,
  • Ian S.D. Roberts,
  • Clare L. Verrill,
  • Lisa Browning

Publication: European Urology, Volume 75, Issue 5, May 2019, Pages 861-867

DOI: https://doi.org/10.1016/j.eururo.2018.12.011

The role of percutaneous renal tumour biopsy (RTB) in the management of radiological indeterminate renal masses is long established. Patients with small renal masses who have biopsy-proven renal cell carcinoma (RCC) may be offered surgery, ablative therapy, or active surveillance, and RTB can provide diagnostic tissue from patients with metastatic disease who might benefit from systemic therapy. Current guidelines suggest that tumour seeding along the needle tract is anecdotal, but several cases have been reported recently, although some have been associated with lack of a coaxial sheath. We report on seven patients who underwent surgical resection of RCC in our tertiary referral institution following diagnostic RTB between 2014 and 2017 for whom RTB tract seeding by tumour was identified on histological examination of the resection specimen. One of these patients subsequently developed local tumour recurrence at the site of the previous biopsy.